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Editor's Correspondence
Sep 26, 2011

Long-term Renal Outcomes of Patients With Type 1 Diabetes Mellitus and Microalbuminuria: An Analysis of the DCCT/EDIC Cohort—Reply

Author Affiliations

Author Affiliations: Department of Medicine, Division of Nephrology, University of Washington, Seattle.

Arch Intern Med. 2011;171(17):1596-1597. doi:10.1001/archinternmed.2011.414

In reply

Gosmanov and Gosmanova thoughtfully note that we focus on environmental risk factors in our recent analysis of long-term renal outcomes of microalbuminuria in the DCCT/EDIC Study, excluding genetic risk factors. They suggest that DCCT/EDIC is an ideal population to address the interaction of environmental and genetic contributors to diabetes complications in order to move the field closer to the application of personalized medicine. We agree that DCCT/EDIC offers unique opportunities to advance genetic medicine but believe that it also exemplifies the difficulties in this endeavor.

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