The analyses and experiments embodied in this paper comprise the second stage of the work on the nature of goiter, viz.: the relation of iodin to the structure of the thyroid gland.In previous papers one of us1 discussed the structure of the thyroid in its various phases in the attempt to formulate basic anatomic types to which the individual glands could be referred. It was found that the various types of changes are quite easily separated into four natural groups, viz.:
(1) Normal glands.
(2) Glandular hyperplasias, all degrees (parenchymatous hypertrophies).
(3) Colloid glands, goiter (all degrees).
(4) Complications supervening in any of the three preceding groups.
MARINE D, WILLIAMS WW. THE RELATION OF IODIN TO THE STRUCTURE OF THE THYROID GLAND.. Arch Intern Med (Chic). 1908;I(IV):349-384. doi:10.1001/archinte.1908.00050030002001