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Editor's Correspondence
August 10, 2009

Fluconazole Use as an Important Risk Factor in the Emergence of Fluconazole-Resistant Candida glabrata Fungemia

Arch Intern Med. 2009;169(15):1444-1445. doi:10.1001/archinternmed.2009.243

We read with interest the article by Lee et al,1 who conducted a case-case-control study to evaluate risk factors for fungemia caused by fluconazole-resistant Candida glabrata. The authors identified previous fluconazole use (and linezolid use) as a significant risk factor for fluconazole-resistant C glabrata fungemia, whereas cefepime and metronidazole use were independent risk factors for fluconazole-susceptible C glabrata fungemia.

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