We would like to thank both respondents for their interest in our article1 and for their valuable remarks. We fully agree that despite the long follow-up period of the study, our data lack statistical power to support final recommendations. We therefore refrained from overly firm conclusions. Still, we believe that based on our findings further investigations are warranted.
Torn M, Rosendaal FR. Optimal Anticoagulation Therapy in Patients With Valvular Heart Disease or Atrial Fibrillation—Reply. Arch Intern Med. 2009;169(21):2033. doi:10.1001/archinternmed.2009.421