In a patient with diabetic ketoacidosis complicated by severe elevation of plasma triglyceride concentrations, treatment with low-level intravenous unfractionated heparin led to prompt reduction in plasma triglyceride concentration and may have prevented the development of hypertriglyceridemia-associated acute pancreatitis. This article reviews the rationale for this treatment and surveys prior publications using heparin in this and similar settings.
Cole RP. Heparin Treatment for Severe Hypertriglyceridemia in Diabetic Ketoacidosis. Arch Intern Med. 2009;169(15):1439-1441. doi:10.1001/archinternmed.2009.221