Author Affiliations: Département de Médecine Aigüe Spécialisée, Hôpital Raymond-Poincaré, Assistance Publique–Hôpitaux de Paris, Garches, France (Dr Crémieux); Université Versailles Saint-Quentin, Faculté de Médecine, Paris Île-de-France Ouest, Versailles France (Drs Crémieux, d’Almeida, and Lert); and INSERM U1018, Centre de Recherche en Épidémiologie et Santé des Populations, Villejuif, France (Drs d’Almeida and Lert).
The first remark by Yazdanpanah et al applied the undiagnosed-infection prevalence observed in the metropolitan Paris emergency departments (EDs) (0.14%) to all persons aged 18 to 64 years in France and claimed that national undetected human immunodeficiency virus (HIV) infections reach 56 000. Because the number of diagnoses per Paris-area inhabitant is 4 times higher than in other regions, that calculation largely overestimates the national prevalence. We would rather conclude that the undiagnosed infection prevalence in France is far below the Centers for Disease Control and Prevention–recommended 0.10% threshold for performing nontargeted screening.1
Crémieux A, d’Almeida KW, Lert F. Nontargeted HIV Screening in Emergency Departments—Reply. Arch Intern Med. 2012;172(6):522-523. doi:10.1001/archinternmed.2012.52