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Editor's Correspondence
Apr 9, 2012

A Multidimensional Prognostic Index in Common Conditions Leading to Death in Older Patients

Author Affiliations

Author Affiliations: Geriatrics Unit, S Antonio Hospital, Padova, Italy (Dr Pilotto); Geriatric Unit and Gerontology–Geriatric Research Laboratory, IRCCS Casa Sollievo della Sofferenza, San Giovanni Rotondo, Italy (Drs Pilotto and Panza); and Clinical Research Branch, National Institute on Aging, Baltimore, Maryland (Dr Ferrucci).

Arch Intern Med. 2012;172(7):595-596. doi:10.1001/archinternmed.2011.1891

We read with interest the study of Siontis and colleagues,1 which reported that, during 2009, among 118 different clinical prediction rules (CPRs) designed to estimate the risk of all-cause mortality, only 10 were studied in 4 or more separate groups of patients, and of these, only 1 CPR was reasonably accurate across all studies.1 Among the 118 CPRs selected for this study, there was also the Multidimensional Prognostic Index (MPI), derived from a standardized Comprehensive Geriatric Assessment, and developed and validated in 2 independent cohorts of older patients hospitalized for acute disease or relapse of a chronic disease, with a close agreement between the estimated and the observed mortality after both 6 months and 1 year of follow-up.2

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