We appreciate Dr Tran’s interest in our article1 and welcome this opportunity to clarify the issues raised by him. Exclusion criteria for our study included a personal history of thyroid disease as well as current or prior treatment of thyroid disease. In addition, baseline thyrotropin (TSH) levels were obtained on all study subjects at week 0. Patients with abnormal TSH levels were excluded from the study.
Mehandru S, Bini EJ. The Uncertain Natural History of Thyrotoxic Patients Treated With Combination Interferon Alfa-2β and Ribavirin—Reply. Arch Intern Med. 2005;165(9):1072-1073. doi:10.1001/archinte.165.9.1072-b