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Editor's Correspondence
June 11, 2012

Black Tea and Blood Pressure: Did the Blood Pressure Fall or Rise?—Reply

Author Affiliations

Author Affiliations: School of Medicine and Pharmacology, University of Western Australia, Perth, Western Australia, Australia (Drs Hodgson and Croft); and Discipline of General Practice, Flinders University, Adelaide, South Australia, Australia (Dr Woodman).

Arch Intern Med. 2012;172(11):894-895. doi:10.1001/archinternmed.2012.1552

In reply

We agree that interpreting the effects of within-group changes in a randomized controlled trial can be problematic. In such trials, outcomes can change over time for reasons unrelated to the intervention. Therefore, drawing conclusions from within-group changes is dangerous. Fortunately, the inclusion of a control group generally overcomes these problems and allows observed differences between groups to be interpreted as the effect of the intervention, regardless of the direction of changes within each of the individual groups.

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