The article by Fredrickson et al and accompanying Invited Commentary by Edlow in this issue of the Archives highlight a disease entity that can be difficult to diagnose but easily treated if diagnosed early. Recently, I seem to have had increasingly frequent discussions with colleagues and patients about Lyme disease. In addition to submissions for this series highlighting the cardiac sequelae that are rare, discussions have included whether to treat a rash without a known tick bite from a high-prevalence area and whether a rash that developed within a few hours of a tick bite was due to infection or a hypersensitivity reaction.
Tabas JA. Recognition of Lyme in Time: Comment on “Infecting the Electrocardiogram”. Arch Intern Med. 2012;172(21):1627. doi:10.1001/2013.jamainternmed.685