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Editor's Correspondence
June 24, 2013

Transfusion in Myocardial Infarction: Bloodcurdling?

Author Affiliations

Author Affiliations: Department of Intensive Care Medicine, VU Medical Centre (Dr Tuinman), and Department of Intensive Care Medicine, Academic Medical Centre (Drs Muller and Juffermans), Amsterdam, the Netherlands.

JAMA Intern Med. 2013;173(12):1156-1157. doi:10.1001/jamainternmed.2013.6515

We read with interest the meta-analysis of Chatterjee and colleagues,1 which reports higher rates of mortality and myocardial reinfarction in patients with myocardial infarction (MI) receiving a blood transfusion. These findings can be added to previous evidence for a restrictive transfusion policy in critically ill patients. As a possible mechanism for the association between transfusion and reinfarction in their meta-analysis, the authors suggest triggering of platelet aggregation by red blood cell transfusion.2

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