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According to a 2011 definition from the Institute of Medicine, clinical practice guidelines provide “recommendations intended to optimize patient care,” and “are informed by a systematic review of evidence and an assessment of the benefits and harms of alternative care options.” It has been known for years that the quality of guidelines varies considerably. The guidelines that best serve the interests of patients and physicians are those that are formulated by independent experts without funding from industry or others with self-interest in the outcome and that are based on rigorous but readily understood methods.1
Steinbrook R. Improving Clinical Practice Guidelines. JAMA Intern Med. 2014;174(2):181. doi:10.1001/jamainternmed.2013.7662