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Comment & Response
February 2014

Conflicts of Interest in Approvals of Food Additives

Author Affiliations
  • 1International Center for Regulatory Science, University of Southern California School of Pharmacy, Los Angeles
  • 2International Food Information Council, Washington, DC
JAMA Intern Med. 2014;174(2):299-300. doi:10.1001/jamainternmed.2013.12723

To the Editor The article by Neltner et al1 raises concerns about the integrity of the “Generally Recognized as Safe” (GRAS) process.

The United States has the most robust assessment of food ingredient safety in the world. The current GRAS process relies on scientific expert consensus, publicly available information, and clinical data. GRAS ingredients have been consumed for decades, and none has compromised public health.

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