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Comment & Response
February 2014

Vertebral Augmentation for Symptomatic Compression Fractures Is Supported by Randomized Clinical Trials

Author Affiliations
  • 1Department of Interventional Radiology, Northside Hospital, Atlanta, Georgia
  • 2Clinical Radiology of Oklahoma, Edmond
JAMA Intern Med. 2014;174(2):307. doi:10.1001/jamainternmed.2013.13035

To The Editor We read with interest the Invited Commentary by Dr Bauer.1 We believe there are portions of his comments that lack scientific support.

The author states that “Although uncontrolled studies have consistently demonstrated reduced short-term pain and disability after vertebral augmentation, randomized trial results have been inconsistent.”1(p1522) In fact, if all Oxford level I and level II data are considered, there are 27 studies, including 8 randomized clinical trials. This collection of articles shows significant reductions in pain, improvement in quality of life, fewer subsequent fractures, and greater kyphosis reduction.2

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