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Comment & Response
March 2014

Caution Warranted When Defining Contraindications in Initiating β-Blocker Therapy

Author Affiliations
  • 1Department of Pharmacy, Jackson Memorial Hospital, Miami, Florida

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Intern Med. 2014;174(3):481. doi:10.1001/jamainternmed.2013.13698

To the Editor Dharmarajan and colleagues1 are to be commended for their review of hospitalized patients with acute decompensated heart failure initiated on β-blocker therapy during predefined periods of clinical instability, which showed that at least 40% of those initiated had at least 1 possible contraindication (care in an intensive care unit, administration of intravenous loop diuretic on the day of discharge, or having received an intravenous inotrope during hospitalization).

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