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Invited Commentary
May 2014

Aspirin as Adjuvant Therapy for Stage III Colon CancerStandard of Care?

Author Affiliations
  • 1Department of Medicine and Herbert Irving Comprehensive Cancer Center, College of Physicians and Surgeon, and Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, New York
JAMA Intern Med. 2014;174(5):739-741. doi:10.1001/jamainternmed.2013.14544

When one sees a patient newly diagnosed as having cancer, after finishing the initial discussion and treatment plan, it is almost inevitable that the patient or a family member will inquire, “What else should he [or she] do?” The implication is that, aside from whatever benefits orthodox therapy—surgery, chemotherapy, radiotherapy—may confer, there are also additional benefits to be gained from lifestyle or behavioral changes, such as diet. I suppose that such beliefs stem from the remarkable benefits in this arena that one can see in cardiovascular disease, where diet, physical activity, and aspirin use are all routine, well accepted, and evidence-based parts of the post–myocardial infarction management landscape. It is no wonder that a patient with breast, colon, prostate, or lung cancer should not anticipate that similar recommendations would be forthcoming.1

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