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Comment & Response
July 2014

Estimating Overdiagnosis in Lung Cancer Screening

Author Affiliations
  • 1Division of Pulmonary and Critical Care Medicine, Weill Cornell Medical Center, New York, New York

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Intern Med. 2014;174(7):1197-1198. doi:10.1001/jamainternmed.2014.1535

To the Editor Patz et al1 attempt to report on the rate of overdiagnosis that occurred as part of the National Lung Cancer Screening Trial (NLST), however their conclusion that “the probability is 18.5%…that any lung cancer detected by LDCT [low-dose computed tomography] was an overdiagnosis”1(p269) is very misleading.

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