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To the Editor Patz et al1 attempt to report on the rate of overdiagnosis that occurred as part of the National Lung Cancer Screening Trial (NLST), however their conclusion that “the probability is 18.5%…that any lung cancer detected by LDCT [low-dose computed tomography] was an overdiagnosis”1(p269) is very misleading.
Gelbman BD, Libby DM. Estimating Overdiagnosis in Lung Cancer Screening. JAMA Intern Med. 2014;174(7):1197-1198. doi:10.1001/jamainternmed.2014.1535