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Comment & Response
October 2014

Improving Medication Adherence and Helping Patients Make Lifestyle Changes—Reply

Ariel Cohen, MD, PhD1; Patrick Assyag, MD2; Isabelle Boutron, MD, PhD3,4,5; et al for the Réseau Insuffisance Cardiaque (RESICARD) PREVENTION Investigators
Author Affiliations
  • 1Service de Cardiologie, Hôpital Saint-Antoine, Assistance Publique des Hôpitaux de Paris (AP-HP), Université Pierre et Marie Curie, Paris, France
  • 2Currently in private practice, Paris, France
  • 3Centre d’Epidémiologie Clinique, Hôpital Hôtel Dieu, Assistance Publique des Hôpitaux de Paris, Paris, France
  • 4Institut National de la Santé et de la Recherche Médicale Unité 738, Paris, France
  • 5Faculté de Médecine, Université Paris Descartes, Sorbonne Paris Cité, Paris, France

Copyright 2014 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.

JAMA Intern Med. 2014;174(10):1708-1709. doi:10.1001/jamainternmed.2014.651

In Reply In response to the comments by Bernal et al, we agree that patient adherence to guideline-based medications in acute coronary syndromes (ACS) remains suboptimal and has been poorly studied. We regret that we have only limited answers to the questions and suggestions raised.1 First, we did not measure medication adherence or intervention by a pharmacist, since the main objective of our study was to examine the impact of an educational program on patient risk factors. Second, we did not prospectively collect data on the percentage of patients who stopped taking their medications. We are eager to read the results of the ongoing study by Bernal et al.2

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