Editor's Correspondence
April 13, 1998

Group A Streptococcal Meningitis

Author Affiliations

Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998

Arch Intern Med. 1998;158(7):810-814. doi:

Since the mid-1980s, there has been an increasing incidence of invasive infections caused by group A β-hemolytic streptococcus (GAS).1 Invasive GAS infections are defined by the isolation of GAS from a normally sterile site in the setting of bacteremia without a focus or focal infections with or without bacteremias, including meningitis, pneumonia, peritonitis, puerperal fever, osteomyelitis, septic arthritis, necrotizing fasciitis, surgical wound infections, erysipelas, and cellulitis.2 Conditions associated with increased risk of invasive GAS include human immunodeficiency virus, malignant neoplasm, heart or lung disease, diabetes mellitus, and alcoholism.1 Meningitis caused by this organism is still very rare and accounts for less than 1% of all meningitides.3 We recently treated a middle-aged woman who developed meningitis after untreated otitis media and recovered fully.

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