The review article on doxycycline by Joshi and Miller1 was not only interesting but also valuable—particularly in this time of managed care and cost containment. Doxycycline is an effective and well-studied drug that is now quite cost competitive—although I still remember when it was first released more than 20 years ago at the extraordinary cost of $1 per capsule.
Tice AD. Doxycycline: New Ways to Use an Old Antibiotic. Arch Intern Med. 1998;158(8):928–929. doi: