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Comment & Response
November 2014

Risks and Benefits of Antihypertensive Medications in Older Adults

Author Affiliations
  • 1HealthPartners Institute for Education and Research, Minneapolis, Minnesota
  • 2Kaiser Permanente of Georgia, Atlanta, Georgia
  • 3University of California, San Francisco
JAMA Intern Med. 2014;174(11):1873. doi:10.1001/jamainternmed.2014.4517

To the Editor The recent observational study by Tinetti et al1 reported that treatment with antihypertensive medications is associated with an increased risk of serious fall injuries among community-living older adults with a mean age of 80 years. One reason for this study was to examine a population that may be less healthy than those enrolled in clinical trials and who may have had a higher risk of serious injuries from falls. Approximately 9% of the cohort experienced a serious injury over the follow-up period, most of which were fractures. Although the mean follow-up time is not stated, the annual rate of fractures appears to have been approximately 1.5% to 2.0%.

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