To the Editor The recent observational study by Tinetti et al1 reported that treatment with antihypertensive medications is associated with an increased risk of serious fall injuries among community-living older adults with a mean age of 80 years. One reason for this study was to examine a population that may be less healthy than those enrolled in clinical trials and who may have had a higher risk of serious injuries from falls. Approximately 9% of the cohort experienced a serious injury over the follow-up period, most of which were fractures. Although the mean follow-up time is not stated, the annual rate of fractures appears to have been approximately 1.5% to 2.0%.
Margolis KL, Barzilay JI, Schwartz AV. Risks and Benefits of Antihypertensive Medications in Older Adults. JAMA Intern Med. 2014;174(11):1873. doi:10.1001/jamainternmed.2014.4517