Copyright 1998 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.1998
Nifedipine therapy administered sublingually or swallowed during treatment of hypertensive emergencies and pseudoemergencies has been widely used in the last decade. Severe adverse effects including symptomatic hypotension,1 stroke,2 ST-segment depression, ventricular fibrillation,3 and myocardial infarction have been reported.4 We describe herein a patient who developed anaphylaxis after receiving sublingual nifedipine for pseudoemergency hypertensive treatment.
Pedro-Botet J, Mínguez S, Supervía A. Sublingual Nifedipine–Induced Anaphylaxis. Arch Intern Med. 1998;158(12):1378-1379. doi: