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A 50-year-old man with cerebral palsy presented to the emergency department with a witnessed generalized tonic-clonic seizure. He had a known seizure disorder that previously had been well controlled with valproate sodium. On transfer, he had multiple seizures, which eventually terminated with intravenous lorazepam in the emergency department. His blood pressure was 70/40 mm Hg, and his Glasgow Coma Scale was 6. He was intubated to protect his airway. A chest radiograph demonstrated extensive airspace opacities at the bases bilaterally, causing concern for aspiration, and he was started on treatment with piperacillin-tazobactam.
Joundi RA, Wong BM, Leis JA. Antibiotics “Just-In-Case” in a Patient With Aspiration Pneumonitis. JAMA Intern Med. 2015;175(4):489-490. doi:10.1001/jamainternmed.2014.8030