We agree with Dr Lesser and colleagues that our findings may underestimate the frequency of ADEs among NH residents. The authors also raise some potential explanations for the increased rate of ADEs among new residents and offer clear opportunities for interventions to reduce the risk for this group.
We regret the confusion around our use of the term "significant." Unfortunately, this term has multiple usages and has been a defined category for the severity of ADEs since the groundbreaking work of Bates and others.1,2 We continue to use this term to ensure that readers following the progress of research in this area will understand the parallels to earlier studies.
Field TS, Gurwitz J. Underestimation of Adverse Drug Events in Nursing Home Residents—Reply. Arch Intern Med. 2002;162(5):609-610. doi: