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Editor's Correspondence
April 22, 2002

Full Adherence to HAART: Is It Really Necessary?—Reply

Arch Intern Med. 2002;162(8):945. doi:

In reply

We thank Drs Cainelli and Vento for their interest in our study. They question the necessity of suppressing HIV RNA in plasma to below 5000 to 11 000 copies/mL during antiretroviral therapy to prevent the development of viral resistance and disease progression among asymptomatic HIV-1–infected patients with reasonably maintained CD4 cell counts. Consequently, they also question the necessity of full adherence to HAART in these patients, since this is required for viral suppression.

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