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Editor's Correspondence
June 10, 2002

Drug-Induced Neutropenias: All Are Not Alike

Arch Intern Med. 2002;162(11):1310-1311. doi:

I would like to offer the following comment to the short article in the November 26, 2001, issue of ARCHIVES by Drs Andrès and Maloisel1 titled "Antibiotic-Induced Agranulocytosis: A Monocentric Study of 21 Cases." The authors describe a study in one center of 21 cases of agranulocytosis and make the following comments: (1) the mortality rate, 5%, was low compared with previously reported mortality rates, which have ranged between 6% and 20%; (2) granulocyte colony-stimulating factor (G-CSF) treatment of agranulocytosis may improve the prognosis and shorten the neutropenia time.1

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