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Editor's Correspondence
June 10, 2002

Drug-Induced Neutropenias: All Are Not Alike—Reply

Author Affiliations

Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002

Arch Intern Med. 2002;162(11):1310-1311. doi:

In reply

We disagree with the comments of Palmblad concerning our article on antibiotic-induced agranulocytosis.

First, Palmblad reports that the neutropenia time and the mortality varies with the drug. But in a multivariable analysis of 91 cases of nonchemotherapy drug–induced agranulocytosis, we have shown that the time of neutropenia (time for neutrophil count to reach >0.5 × 109/L), which is indirectly related to mortality, was not influenced by the type of drugs (unpublished data, 2001).

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