Clinical Observation
September 23, 2002

Bilateral External Laryngoceles Following Radioiodine Ablation for Graves Disease

Author Affiliations

From the Endocrine-Metabolic Service (Drs Stocker, Bernet, and Burch) and Pulmonary–Critical Care Service (Drs Kelly and Fitzpatrick), Department of Medicine, Walter Reed Army Medical Center, Washington, DC.


Copyright 2002 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2002

Arch Intern Med. 2002;162(17):2007-2009. doi:10.1001/archinte.162.17.2007

A 28-year-old trumpet player underwent multiple treatments with radioactive iodine for Graves disease associated with an unusually large goiter. Following his second treatment, the patient developed acute neck pain and swelling. Radiographic studies and a laryngoscopy demonstrated bilateral symptomatic external laryngoceles, a very rare entity, not previously known to be associated with radioiodine treatment or Graves disease. The patient's profession placed him at risk for the development of a laryngocele, but the temporal relationship to goiter regression following radioiodine therapy suggests that this occurred as a result of this treatment. The patient's disease was managed nonsurgically, and he has subsequently done well. This represents the first known association of symptomatic laryngocele with radioiodine treatment for Graves disease.