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Editor's Correspondence
March 24, 2003

Is MRSA More Pathogenic in Critically Ill Patients?

Arch Intern Med. 2003;163(6):739-740. doi:10.1001/archinte.163.6.739

I read with great interest the recent Original Investigation "Outcome and Attributable Mortality in Critically Ill Patients With Bacteremia Involving Methicillin-Susceptible [MSSA] and Methicillin-Resistant Staphylococcus aureus [MRSA]."1

The attributable mortality rates in intensive care unit (ICU) patients with staphylococcal bacteremia obtained in this study by using 2 independent case-control studies is clearly unique to this study. Even though the study did not specifically use hemodynamic instability, acute renal failure, and MRSA bacteremia as explanatory variables, it has established these statistically as independent predictors of mortality.

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