We have read with interest the case report of Chiodera et al,1 which addresses the issue of the differential diagnosis of corticotropin-dependent Cushing syndrome. It provides us a fine example of how challenging this task might be and underscores the merit of continuing clinical and biochemical evaluation in equivocal cases. A second biochemical assessment may draw out more apparent data than the one at baseline, as it occurred in their case. This is an important practical message to be applied whenever patient conditions allow an expectant management.
Terzolo M, Reimondo G, Angeli A. Desmopressin Test in Mild Cushing Syndrome. Arch Intern Med. 2003;163(7):850-851. doi:10.1001/archinte.163.7.850