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Editor's Correspondence
June 23, 2003

Thalidomide Has Activity in Treating Complex Regional Pain Syndrome—Reply

Author Affiliations

Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2003

Arch Intern Med. 2003;163(12):1488. doi:10.1001/archinte.163.12.1487

In reply

We are pleased that studies by Schwartzman et al confirm our initial case report describing the complete resolution of reflex sympathetic dystrophy (or CRPS) with thalidomide therapy.1 The patient we described is doing well and continues to receive thalidomide for the treatment of myeloma at a maintenance dose of 100 mg/d. With a current follow-up of 30 months, she remains asymptomatic and has no recurrence of CRPS. We fully concur with the plan by Schwartzman et al to initiate a multicenter, randomized trial to further define and establish the role of thalidomide for this serious and disabling condition.

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