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Editor's Correspondence
November 24, 2003

Risk of Unexplained Acute Liver Failure in Diabetes Mellitus

Author Affiliations

Copyright 2003 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2003

Arch Intern Med. 2003;163(21):2649-2650. doi:10.1001/archinte.163.21.2649-a

The study by Chan et al1 sought to estimate the incidence of acute liver failure (ALF) and injury unrelated to other causes among patients with diabetes mellitus treated with oral agents or insulin. Several shortcomings in their analysis and presentation of the data promote an inaccurate understanding of the issue of acute liver failure and non-ALF acute liver injury (ALI) in patients receiving treatment for diabetes.

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