We were pleased to read that Dr Christensen could reproduce our recently published results1 in her cohort of patients with stroke. In fact, she published that within the first hours after stroke, the blood pressure is significantly higher in patients with mild to moderate cerebral infarction than in patients with severe cerebral infarction.2 The blood pressure fell more in the former than in the latter, and a few hours later the difference disappeared. In her correspondence, she adds that the proportion of patients with lacunar infarction is much larger among the former than among the latter (38.2% vs 6.8%), confirming our data showing that patients with lacunar infarction had a mild stroke and a marked blood pressure elevation. Accordingly, a large proportion of her patients with severe ischemic stroke may have had cardioembolic or atherosclerotic stroke and a lower blood pressure during the first hours after admission, again in agreement with our data.
Semplicini A, Sartori M. Hypertension in Acute Stroke—Reply. Arch Intern Med. 2003;163(21):2652. doi:10.1001/archinte.163.21.2651