Weintrob et al1 recently pointed out the infrequency in diagnosis of primary human immunodeficiency virus (HIV) infection by performing HIV RNA polymerase chain reaction (PCR) in patients who present with viral syndrome and have risk factors for HIV infection. However, they do not address cost-effectiveness of this strategy and the use of empirical antiretroviral therapy.
Tanvetyanon T. Screening for Primary Human Immunodeficiency Virus Infection. Arch Intern Med. 2004;164(6):680. doi:10.1001/archinte.164.6.680-a