The discussion by Hirschmann and colleagues1 on Herod’s cause of death took into account information provided by Josephus in the War of Jews.2 After reviewing Josephus’ Antiquities of the Jews,2 we came across 2 prominent and rare symptoms that may suggest a different explanation for Herod’s death: platypnea and a voracious appetite.
Madariaga MG, Smith PW. Infectious Disease Consultation for Herod the Great. Arch Intern Med. 2004;164(22):2500-2509. doi:10.1001/archinte.164.22.2507-b