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Comment & Response
April 2015

Effect of Wine Consumption on Mortality—Reply

Author Affiliations
  • 1Department of Ophthalmology, The Johns Hopkins University School of Medicine, Baltimore, Maryland
  • 2Nutrition and Food Science Department, Biomarkers & Nutrimetabolomics Laboratory, Food Technology Reference Net and Nutrition and Food Safety Research Institute (XaRTA, INSA), Pharmacy School, University of Barcelona, Barcelona, Spain
  • 3Unit of Nutrition, Environment and Cancer, Cancer Epidemiology and Research Programme, Catalan Institute of Oncology (ICO-IDIBELL), Barcelona, Spain
JAMA Intern Med. 2015;175(4):651. doi:10.1001/jamainternmed.2014.8078

In Reply In the original analysis in our article,1 we found no significant relationship between quartiles of total urinary resveratrol metabolites and all-cause mortality in the multivariable Cox proportional hazards models after adjusting for sex and other potential confounders. We have performed the analyses stratified by sex, as requested by Glaser. The results show that there was no significant relationship between quartiles of total urinary resveratrol metabolites and all-cause mortality for either men or women (Table). This additional analysis shows no differences by sex between resveratrol and mortality.

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