We read with interest the article by de Perio et al1 regarding the cost-effectiveness of screening for latent tuberculosis in health care workers. We commend their analysis of an important topic and find most of the analysis and results reasonable. However, readers should be cautioned that several of the assumptions used in their model are inconsistent with more recently published data.2 These differences may invalidate some of their conclusions that new blood tests for tuberculosis are both “more effective and less costly” than tuberculin skin testing (TST).
Mancuso J, Niebuhr D, Krauss MR, Dabbs C, Anderson K. Cost-effectiveness of Tuberculosis Screening in Health Care Workers Is Not Robust. Arch Intern Med. 2009;169(14):1336-1340. doi:10.1001/archinternmed.2009.211