[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 4,203
Citations 0
Teachable Moment
Less Is More
June 2015

Nonsteroidal Anti-inflammatory Drug Use in a Patient With HypertensionA Teachable Moment

Author Affiliations
  • 1Division of Immunology, University of Iowa, Iowa City
  • 2Division of Nephrology, University of Iowa, Iowa City
JAMA Intern Med. 2015;175(6):892-893. doi:10.1001/jamainternmed.2015.0809

A man in his 60s with hypertension, hyperlipidemia, and knee osteoarthritis presented with fatigue, decreased exercise tolerance, and worsening bilateral leg swelling. For 5 years, he had been prescribed lisinopril, simvastatin, and meloxicam as needed for pain. Over the past 3 months, he had been taking meloxicam, 15 mg daily, for worsening knee pain following a minor fall that led to a persistent sense of discomfort that limited him from pursuing recreational activities like biking and running but did not otherwise prevent him from performing his activities of daily living. He had not tried acetaminophen or other pain relievers before. During this same time, his lisinopril dose was doubled to 20 mg daily because his blood pressure had been slowly rising.

First Page Preview View Large
First page PDF preview
First page PDF preview