Rensing and colleagues raise an important question in regard to insulin therapy among hyperglycemic patients hospitalized for AMI. Based on the statistically insignificant but quantitatively higher in-hospital mortality across several of our predefined mean glucose categories,1 they suggest that insulin may be associated with increased mortality risk.
Kosiborod M, Inzucchi SE, Krumholz HM, Masoudi FA, Goyal A, Spertus JA. Is Insulin the Preferred Compound in Lowering Glucose Levels in Patients After a Myocardial Infarction?—Reply. Arch Intern Med. 2009;169(17):1633-1638. doi:10.1001/archinternmed.2009.327