Acute pancreatitis is a devastating disease, causing over 200 000 hospitalizations in the United States annually. A cause of extensive morbidity, the per-incident mortality rate of acute pancreatitis is approximately 5%. With no pharmacologic intervention that has proven reliable in improving clinical outcomes, it is imperative that clinicians recognize patients with a predicted severe outcome early in their course. Early recognition of severity allows for appropriate triage to the intensive care unit, adequate fluid resuscitation, and initiation of enteral feedings.
Gardner TB. BUN Level as a Marker of Severity in Acute Pancreatitis: Simple, Universal, and AccurateComment on “Blood Urea Nitrogen in the Early Assessment of Acute Pancreatitis”. Arch Intern Med. 2011;171(7):676-677. doi:10.1001/archinternmed.2011.125