To the Editor We read with great interest the case series describing occurrence of spontaneous coronary artery dissection (SCAD) in pairs of related individuals from 5 families.1 Familial clustering of such a rare clinical event implies the possibility of genetically determined susceptibility factors in the pathogenesis of SCAD.
We too noticed the phenomenon of a pair of SCAD cases in a mother and daughter treated at our institution.
White AJ, Malaiapan Y, Meredith IT. Another Report of Familial Spontaneous Coronary Artery Dissection. JAMA Intern Med. 2015;175(10):1721. doi:10.1001/jamainternmed.2015.3824