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Comment & Response
October 2015

Vitamin D Supplements and the Risk of Falls—Reply

Author Affiliations
  • 1Kaiser Permanente Research Affiliates Evidence-Based Practice Center, Portland, Oregon
  • 2Center for Health Research, Kaiser Permanente NW, Portland, Oregon
  • 3Pacific Northwest Evidence-Based Practice Center, Oregon Health & Science University, Portland
JAMA Intern Med. 2015;175(10):1724. doi:10.1001/jamainternmed.2015.3965

In Reply Bolland and colleagues question the inclusion of trials of vitamin D analogues in our meta-analysis. This meta-analysis was an update of prior meta-analyses conducted for the US Preventive Services Task Force (USPSTF) to inform recommendations on use of vitamin D for prevention of falls in primary care settings.1,2 As in the prior USPSTF analyses, we included trials that evaluated vitamin D analogues and did not exclude them on a post hoc basis. Inclusion of vitamin D and vitamin D analogues is appropriate given the similar mechanisms and action and variability in how vitamin D deficiency is treated.

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