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Editor's Correspondence
May 9, 2005

Serum Ferritin Levels in Patients With Nonalcoholic Fatty Liver Disease

Arch Intern Med. 2005;165(9):1070. doi:10.1001/archinte.165.9.1070-a

Kim and colleagues1 evaluated the metabolic factors associated with nonalcoholic fatty liver disease (NAFLD). However, they did not consider serum ferritin levels. There is a growing body of evidence that serum ferritin, a good indicator of body iron stores, is associated with both metabolic syndrome2 and NAFLD.3 Although a potential beneficial role of iron depletion is questionable,4 it might be wise advising patients with NAFLD to modify their diets5,6 by minimizing consumption of red meat (a rich source of heme iron) and alcohol, avoiding iron supplementation and restricting their intake of vitamin C (an enhancer of nonheme iron absorption).