To the Editor The DANTE study1 provided data of high clinical significance considering that it is the very first study evaluating the effect of antihypertensive treatment discontinuation on cognitive function in elderly patients. As mentioned by Moonen et al, the termination of the treatment had no beneficial results on the cognitive, psychological, and general function, even in subgroup analysis based on several factors. We would be obliged to the authors if they performed an additional analysis according to baseline pulse pressure levels and estimated glomerular filtration rate.
Imprialos K, Boutari C, Doumas M. Discontinuation of Antihypertensive Treatment in Elderly Patients and Cognitive Function. JAMA Intern Med. 2016;176(3):409. doi:10.1001/jamainternmed.2015.8342