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Comment & Response
May 2016

Mixed Diagnoses and Mixed Messages—Reply

Author Affiliations
  • 1Iberoamerican Cochrane Center, Biomedical Research Institute Sant Pau (IIB Sant Pau), Barcelona, Spain
  • 2CIBER de Epidemiología y Salud Pública (CIBERESP), Spain
  • 3Via Roma Primary Care Center, Barcelona, Spain
  • 4Doctor Carles Ribas Primary Care Center, Barcelona, Spain
JAMA Intern Med. 2016;176(5):719. doi:10.1001/jamainternmed.2016.1287

In Reply We thank Dr Linder and Dr Friedberg for their interest in our study. However, we do not agree that antibiotics should never be prescribed in patients with acute bronchitis. As with other respiratory infections, antibiotics may be effective in a subset of patients.1,2 For example, Teepe et al3 found that patients with lower respiratory tract infections with radiologically proven pneumonia not clinically suspected at presentation did benefit from antibiotic treatment. Delayed prescription of antibiotics could be a reasonable option for these patients too.

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