In Reply We thank Dr Linder and Dr Friedberg for their interest in our study. However, we do not agree that antibiotics should never be prescribed in patients with acute bronchitis. As with other respiratory infections, antibiotics may be effective in a subset of patients.1,2 For example, Teepe et al3 found that patients with lower respiratory tract infections with radiologically proven pneumonia not clinically suspected at presentation did benefit from antibiotic treatment. Delayed prescription of antibiotics could be a reasonable option for these patients too.
Alonso-Coello P, Llor C, de la Poza Abad M. Mixed Diagnoses and Mixed Messages—Reply. JAMA Intern Med. 2016;176(5):719. doi:10.1001/jamainternmed.2016.1287