In Reply We appreciate the interest in our work from Zhou and colleagues. The China Kadoorie Biobank is a large population-based prospective cohort study of 0.5 million adults ages 35 to 74 years (when recruited during 2004-2008) from 10 diverse regions of China.1 We reported that about one-third of the participants had hypertension at recruitment, but less than 5% of these hypertensives had their blood pressure properly controlled (<140 mm Hg systolic and <90 mm Hg diastolic blood pressure).1 We estimated that if these findings were broadly representative, then approximately 750 000 cardiovascular deaths could be attributed to uncontrolled hypertension in China in 2010.
Lewington S, Lacey B, Clarke R. Uncontrolled Hypertension and Risk of Cardiovascular Mortality in China—Reply. JAMA Intern Med. 2016;176(8):1234. doi:10.1001/jamainternmed.2016.3825