[Skip to Content]
Access to paid content on this site is currently suspended due to excessive activity being detected from your IP address Please contact the publisher to request reinstatement.
[Skip to Content Landing]
Views 241
Citations 0
Comment & Response
October 2016

Effect Of Detecting and Isolating Asymptomatic Clostridium difficile Carriers—Reply

Author Affiliations
  • 1Jewish General Hospital Sir Mortimer B. Davis, Montreal, Canada
  • 2McGill University Faculty of Medicine, Montreal, Canada
  • 3Institut National de Santé Publique du Québec, Quebec City, Canada
  • 4Centre Hospitalier Universitaire de Québec, Québec City, Canada
  • 5Université Laval, Quebec City, Canada
  • 6McGill University Health Centre, Montreal, Canada
JAMA Intern Med. 2016;176(10):1573. doi:10.1001/jamainternmed.2016.5342

In Reply We thank Crobach and colleagues for their thoughtful comments on our article.1 They raise pertinent questions regarding the mechanisms through which the detection and isolation of C difficile carriers on hospital admission could lead to a decrease in Clostridium difficile infection (CDI) rates. They suggest 3 potential mechanisms: a decrease in the progression from carriage to disease; a decrease in spread from carriers; and a decrease in spread from patients with CDI. It is difficult to ascertain which of these mechanisms may have contributed to the decrease in CDI rates in our hospital.

First Page Preview View Large
First page PDF preview
First page PDF preview