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February 2017

Transcatheter Aortic Valve Replacement in Younger Individuals

Author Affiliations
  • 1Department of Healthcare Policy and Research, Weill Cornell Medicine and New York Presbyterian Hospital, New York, New York
  • 2Section of Cardiovascular Medicine, Veterans Affairs Connecticut Healthcare System, West Haven, Connecticut
  • 3Robert Wood Johnson Foundation Clinical Scholars Program, Yale School of Medicine, New Haven, Connecticut
  • 4Cardiac Surgeon, Blessing Hospital, Chicago, Illinois
JAMA Intern Med. 2017;177(2):159-160. doi:10.1001/jamainternmed.2016.8104

When a patient has an aortic valve that requires replacement because the native valve is diseased, 2 types of valves can be used—mechanical valves or bioprosthetic valves, also known as tissue valves. Bioprosthetic valves are less durable than mechanical values but generally do not require the long-term use of anticoagulation; they are often recommended in older patients. Mechanical valves require therapeutic anticoagulation because of the risk for valve thrombosis, a catastrophic and life-threatening complication. The use of bioprosthetic valves increased from 38% in the period from 1998 to 2001 to 64% in the period from 2007 to 2011.1

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