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Editor's Correspondence
May 8, 2006

The Role of Inflammation for Heart Disease Risk Cannot Be Determined by Correlations Between C-Reactive Protein and Risk Factors

Arch Intern Med. 2006;166(9):1040-1041. doi:10.1001/archinte.166.9.1040-a

I read with interest the recent article by Miller et al.1 The purpose of this cross-sectional study was to “evaluate the extent to which high CRP [C-reactive protein] levels may simply reflect expression of the pathobiological changes induced by conventional CHD [coronary heart disease] risk factors.”1(pp2063-2064) The authors concluded that “These data suggest that elevated CRP level in the general population are in large measure attributable to traditional CHD risk factors.”1(p2063)

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