Controversies in Internal Medicine
May 22, 2006


Author Affiliations



Copyright 2006 American Medical Association. All Rights Reserved. Applicable FARS/DFARS Restrictions Apply to Government Use.2006

Arch Intern Med. 2006;166(10):1071-1072. doi:10.1001/archinte.166.10.1071

I disagree with Dr Raggi on the strength of evidence supporting the practice of routine screening for subclinical atherosclerosis among asymptomatic individuals. The principal differences in interpretation of the data are 2-fold: (1) I believe that there is insufficient measurement of risk factors in most of the available prospective cohort studies against which the new information is compared, and (2) I believe that most of the multivariate analyses are inadequate to assess the true independent prognostic value of this new information.