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Controversies in Internal Medicine
May 22, 2006

Rebuttal

Author Affiliations
 

ANN B.NATTINGERMD, MPH

Arch Intern Med. 2006;166(10):1071-1072. doi:10.1001/archinte.166.10.1071

I disagree with Dr Raggi on the strength of evidence supporting the practice of routine screening for subclinical atherosclerosis among asymptomatic individuals. The principal differences in interpretation of the data are 2-fold: (1) I believe that there is insufficient measurement of risk factors in most of the available prospective cohort studies against which the new information is compared, and (2) I believe that most of the multivariate analyses are inadequate to assess the true independent prognostic value of this new information.

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